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Adding phytoestrogens to clomiphene induction in unexplained infertility patients – a randomized trial

It is concluded that follicular phase phytoestrogens, namely C. racemosa rhizome dry extract, at the given dose and duration, can improve the induction outcomes in unexplained infertility patients who are managed by clomiphene induction and timed intercourse, and who previously received multiple unsuccessful clomiphene induction cycles. This novel regimen could help to save these couples […]

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New insights into male (in)fertility: the importance of NO

Although infertility is a common global problem, treatment is sometimes ineffective, and the number of couples seeking infertility services has increased dramatically over the last decade. Such an increase in infertility rates clearly indicates the need for the development of new strategies to treat sterility. It has become evident that redox regulation in reproductive biology,

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L-arginine enhances cell proliferation and reduces apoptosis in human endometrial RL95-2 cells

L-arginine added to the culture media atphysiological (200 μmol/L) and supraphysiologicalconcentrations (800 μmol/L) enhanced endometrialRL95-2 cell proliferation through mechanisms mediatedby NO and polyamine biosynthesis and by reducingendometrial RL95-2 cell apoptosis through the phosphorylationof BAD protein. Cell proliferation is animportant process in the human endometrium, as theendometrial epithelium must regenerate following thelosses experienced during menstruation in

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